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Next, eliminating Medical marijuana uses. Sorry people who found relief. Profits aren't helping the right people.
That first thing that came to mind was targeting states that did not go for Trump during the election. And if you think about, using his presidential power to influence specific states through punish\reward, would not surprise me. He's got around him people who are thinking differently\dirty about political warfare, and they are throwing out the rules of right\wrong. Their basic thinking is "If a tactic works, then it's right. If the tactic doesn't work, it's wrong. There is no moral evaluation". Hell, pulling\denying federal funds from states that didn't vote for him during the election very much could be on the table in terms of these new politics from Trump's Administration.
If it were possible, you know he would love to trigger an economic depression limited to the state of California, and you could see him tweeting "See what happens to the stupid people of California, they didn't vote for me and now are in deep shit. Sorry, not my problem...call Mexico"