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Mylan is a real mess

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    The EpiPen came about, in part, because of public funding.

    "The EpiPen was designed by Sheldon Kaplan at Survival Technology, Inc. (STI). STI had an existing version of an autoinjector made of stainless steel, but its use was limited and also restricted to drugs only stable in that particular alloy. Instead, Kaplan developed a system that allowed for the use of a glass container, while delivering a larger volume of drug. In 1973, when Kaplan’s design concept was almost complete, the Pentagon approached STI looking for a delivery method for a nerve agent antidote not stable in stainless steel. Kaplan’s invention became the ComboPen for the Department of Defense and the EpiPen for consumers."

    invent.org/media/nihf/docs/Kaplan.pdf

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    Let's also remember that for-profit R&D research produces a lot of unnecessary drugs.

    If all R&D research was expected to be funded through pharmaceutical company revenues modern medicine would not exist and progress in medical research would ground to a halt.

    The entire practice of medicine is a product of public-private partnerships.

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    jaredsxtn Wrote:
    Chet Ruminski Wrote:"EpiPens will become far cheaper once their patent expires."

    There are multiple drugs not protected by patent that are rising daily.

    These sensational accounts are actually dwarfed but the rising cost of all drugs. Including otc.

    What drugs are you talking about? Are these mystery drugs rising due to inflation or because of other factors?

    Price competition comes in once patents expire. That's why acetaminophen and ibuprofen cost pennies on the dollar.

    omeprazole is one. The generic prescription price is now $1.70/pill up 170% in two years at CVS. Function of dealings at Valeant. All hedge fund workings. All too big and too fast to control.
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    We get so absorbed by the protestations for deregulating that we forget that there is a government that is assigned to protect individual citizens . The government has vested power to act as follows:

    According to the standard economic canon, government

    intervention into private business affairs normally is justified under one of the following

    five rubrics:

    1. to create and enforce rules of the game and keep the system honest;

    2. to guard against undue concentration, thus keeping markets competitive;

    3. to redistribute income, e.g., through the tax-and-transfer system;

    4. to correct externalities or other market failures, e.g., those due to asymmetric

    information;

    5. to protect the interests of taxpayers, e.g., in cases in which public money is being spent or put at risk.

    I think we are so bombarded by right wing and big money demands that we forget we have rights and are allowed to say "WTF". But the shut up and be thankful is so overbearing that when somebody does say "WTF" as in the case of Bernie the other victims become apologists and shun the protestor as in the case of Bernie.

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    jaredsxtn Wrote:
    Dutch Wrote: Jared, I guess you better ask your money back for your degree!! Just playing the "patriot" while you are being ripped off by your own fellow country man does not cut it. No CEO of any pharma or health institute here is going hungry. Ask our Mr Scott who made millions ripping off hospitals and then via our fantastic law system could claim the "fifth' a hundred times and managed to become governor via bribe money. Go wave your flag Jared and burn your "degree papers". By the way most drugs used in Europe are produced there; seldom I've seen any US made drug there; they make sure they have equivalent products or licences. Via Novartis, Bayer, and others. Yes the Obamacare is in the "red" read the news.


    Jared you have no clue whatsoever; go find an drug pricelist from here and over there and compare. No Europe has no advantage from the US. None whatsoever.

    Seriously man. Get a grip. Your hatred of America clouds your judgement and makes it impossible to have a fact based conversation with you.

    Jared, you are blinded by your patriotic indoctrination; no Europe does not need the US; they make at least sure the public does not get ripped off like here. Your problem is that you refuse to accept reality.
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    Dutch Wrote: Jared, you are blinded by your patriotic indoctrination; no Europe does not need the US; they make at least sure the public does not get ripped off like here. Your problem is that you refuse to accept reality.
    And you are blinded by your patriotic indoctrination of Holland.

    The vast majority of major pharmaceutical companies are American. The vast majority of prescription drugs Europeans use are American brand name or generic drugs. That. Is. A. Fact.

    I understand facts are really (and I mean REALLY) hard for you to accept sometimes, but the great thing about facts is that they are irrefutable.

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    pharmaceutical-technology.com/features/.../
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    Chet, thanks; again this proves Jared lives in la la land; he knows the facts!! Also just for Jared's sake; we've got plenty of family and friends in the Netherlands who consume drugs. The point Jared does not understand that if the US developes drugs which are sold overseas they are labeled with different names or description because of laws there or licencing agreements. Some contents used in the US are not allowed there as well. Most of the US developed drugs have to be approved under the European standards before they are allowed on the market.. Also there is of course an tax issue. Most of what is used over there is generic anyway. Like Chet says about omeprazole; it has another trade name there. My wife also says that the "quality" of the same European drugs is much better than over here. Indeed with the omeprazole is that the case; that is why she uses the European equivalent.

    Anyway Chets published list is correct; with the exception that the 5 European companies supply in Europe of course more drugs money wise than any US companies. Especially Bayer and Novartis. ( Bayer is missing from the list; how come?)

    Jared, I would take some Bayer low dose aspirins, before you get an heart attack waving your flag way too long.

  • Are you sure you want to delete this post?
        
    Dutch Wrote:

    Chet, thanks; again this proves Jared lives in la la land; he knows the facts!! Also just for Jared's sake; we've got plenty of family and friends in the Netherlands who consume drugs. The point Jared does not understand that if the US developes drugs which are sold overseas they are labeled with different names or description because of laws there or licencing agreements. Some contents used in the US are not allowed there as well. Most of the US developed drugs have to be approved under the European standards before they are allowed on the market.. Also there is of course an tax issue. Most of what is used over there is generic anyway. Like Chet says about omeprazole; it has another trade name there. My wife also says that the "quality" of the same European drugs is much better than over here. Indeed with the omeprazole is that the case; that is why she uses the European equivalent.

    Anyway Chets published list is correct; with the exception that the 5 European companies supply in Europe of course more drugs money wise than any US companies. Especially Bayer and Novartis. ( Bayer is missing from the list; how come?)

    Jared, I would take some Bayer low dose aspirins, before you get an heart attack waving your flag way too long.

    And then Oregon became dead quiet.
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    The Lack of EpiPen Competitors is the FDA's Fault | Mises Wire
    Mises Institute › blog › lack-epipen-com...
    Mobile-friendly - 4 days ago - That friend is the FDA. ... Epinephrine is extremely cheap—just a few cents per dose. ... It's like expecting somebody to come up with a new way to play baseball ... to substitute Adrenaclick as a generic alternative to EpiPen.
    Adrenaclick: Cheaper alternative to EpiPen - Story | FOX 13 Tampa Bay
    www.fox13news.com › 195540999-story
    Mobile-friendly - 4 days ago - Adrenaclick: Cheaper alternative to EpiPen ... why the cost has gone up by 400 percent in the last nine years. ... One competitor got recalled, and two others still wait for FDA approval.
    EpiPen prices are out of control! Here's how we fix the problem ...
    CNBC › 2016/08/23 › epipen-prices-are-...
    Mobile-friendly - 5 days ago - The price of a pack of life-saving EpiPens shot up to $400. ... don't hold up under scrutiny are actually hurting a lot of people. ... In its recall announcement, the FDA stated that Auvi-Q: ...
    Generic EpiPen: What's The Hold-Up? - Teva Pharmaceutical ...
    Seeking Alpha › article › 3881636-gener...
    Mobile-friendly - Feb 10, 2016 - Teva has still not received FDA approval for its generic EpiPen.The company is expected to announce ...
    EpiPen costs have soared 450 percent in the past 12 years, for ...
    Slate › articles › moneybox › 2016/07
    Mobile-friendly - Jul 8, 2016 - In fact, no generic version of the EpiPen is currently available, and the FDA recently blocked a request ...
    Senators to FDA: Where are the Alternatives to Mylan's EpiPen ...
    www.raps.org › News › 2016/08/25 › Se...
    Mobile-friendly - 3 days ago - News reports indicate that generic versions of the EpiPen have been subject to additional questioning ...
    Senators want to know what FDA is doing to make EpiPen rivals ...
    https://www.statnews.com › 2016/08/25
    Mobile-friendly - 3 days ago - Some senators expressed worries to FDA Commissioner Dr. Robert Califf that the agency is not doing ...
    Soaring EpiPen price spurs allergy patients to resort to syringes
    https://www.statnews.com › 2016/07/06
    Mobile-friendly - Jul 6, 2016 - High price of EpiPens spurs consumers, EMTs to resort to syringes for allergic reactions.
    EpiPen outrage may fuel cheap generic in 2017 | Q13 FOX News
    Q13 FOX News › 2016/08/26 › epipen-o...
    Mobile-friendly - 3 days ago - Gal predicted the FDA's review of Teva's alternative may be ... However, the FDA noted that it automatically speeds up review ...
    Senators want answers from FDA on EpiPens - POLITICO
    Politico › politico-pulse › 2016/08 › sena...
    Mobile-friendly - 3 days ago - ... bipartisan group of senators are pressing the FDA to explain what's holding up approval of generic alternatives to EpiPen. ... Pelosi lauds continued access to cheap exchange plans.
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    The real culprit CFMA. The massive shift toward non interested profit taking had created massive amounts of what Mark Cuban calls "phuque you" money. So much money unlimited money that nothing is beyond comprehension. The market needs to start making things to sell to generate profits or who knows what will happen.

  • Are you sure you want to delete this post?
        
    Dutch Wrote:
    Dutch Wrote:

    Chet, thanks; again this proves Jared lives in la la land; he knows the facts!! Also just for Jared's sake; we've got plenty of family and friends in the Netherlands who consume drugs. The point Jared does not understand that if the US developes drugs which are sold overseas they are labeled with different names or description because of laws there or licencing agreements. Some contents used in the US are not allowed there as well. Most of the US developed drugs have to be approved under the European standards before they are allowed on the market.. Also there is of course an tax issue. Most of what is used over there is generic anyway. Like Chet says about omeprazole; it has another trade name there. My wife also says that the "quality" of the same European drugs is much better than over here. Indeed with the omeprazole is that the case; that is why she uses the European equivalent.

    Anyway Chets published list is correct; with the exception that the 5 European companies supply in Europe of course more drugs money wise than any US companies. Especially Bayer and Novartis. ( Bayer is missing from the list; how come?)

    Jared, I would take some Bayer low dose aspirins, before you get an heart attack waving your flag way too long.

    And then Oregon became dead quiet.
    Oregon became quiet because Oregon was enjoying the glorious Pacific Northwest forests with his soon to be bride. There are things in life that are more important than going around in endless circles with people on web forums.
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    Chet Ruminski Wrote: pharmaceutical-technology.com/features/.../

    I'm not entirely sure about the reasoning behind posting this article.

    It shows that five of the ten richest pharmaceutical companies are from the United States while simultaneously refuting Dutch's argument that Pharmaceutical companies in other parts of the globe aren't motivated by profit.

    GlobalData's pharmaceutical revenue figures has a more exhaustive listing of pharmaceutical company profits and sales and it does even more damage to Dutch's arguments.

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    Dutch Wrote: Especially Bayer and Novartis. (Bayer is missing from the list; how come?)

    Bayer is #16.

    Dutch Wrote: Jared, I would take some Bayer low dose aspirins, before you get an heart attack waving your flag way too long.

    I haven't taken a Bayer (aspirin), Tylenol (acetaminophen), Motrin (Ibuprofen), or any other pain reliever/cough suppressant/etc. in over ten years. I long ago decided to see if rest, heat/ice, and other forms of natural remedies would work for me and they have.

    I'm not knocking all pharmaceutical medicines because many are life saving, but I haven't had any medical emergency that has required me to take any medicine since I had my brain hemorrhage in 1997.

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    Some things are just facts I of life. I think that anything life saving should not be denied. I don't know how they managed to make such a mess out of welfare, but it should have been supplemental tied to working with a health plan all health plans and only one level of benefit for everybody. ACA has turned it into a class distinction provider. The right has so distorted the value of life according to classes that people are desensitized to a price on living.