| Ranking Member | | | # | Committee Leadership | Other Committees | |
|---|
| Thad Cochran | (R-MS) | | 4 | Agriculture, Nutrition & Forestry & Appropriations | Rules & Administration & Joint Committee on the Library | 1 |
| James Inhofe | (R-OK) | | 2 | Armed Services | Environment & Public Works | 67 |
| Mike Crapo | (R-ID) | | 5 | Banking, Housing & Urban Affairs | Budget, Environment & Public Works, Finance & Indian Affairs | 2 |
| Jeff Sessions | (R-AL) | | 4 | Budget | Armed Services, Environment & Public Works & Judiciary | 254 |
| John Thune | (R-SD) | | 3 | Commerce, Science & Transportation | Agriculture, Nutrition & Forestry & Finance | 3 |
| Lisa Murkowski | (R-AK) | | 4 | Energy & Natural Resources | Appropriations, Health, Education, Labor & Pensions & Indian Affairs | 3 |
| David Vitter | (R-LA) | | 4 | Environment & Public Works | Armed Services, Banking, Housing & Urban Affairs & Small Business & Entrepreneurship | 41 |
| Orrin Hatch | (R-UT) | | 4 | Finance | Health, Education, Labor & Pensions, Judiciary & Aging | 1 |
| Bob Corker | (R-TN) | | 3 | Foreign Relations | Banking, Housing & Urban Affairs & Aging | 34 |
| Lamar Alexander | (R-TN) | | 6 | Health, Education, Labor & Pensions | Appropriations, Energy & Natural Resources, Rules & Administration, Joint Committee on the Library & Joint Committee on Printing | 1 |
| Tom Coburn | (R-OK) | | 3 | Homeland Security & Government Affairs | Banking, Housing & Urban Affairs & Intelligence | 13 |
| Chuck Grassley | (R-IA) | | 4 | Judiciary | Agriculture, Nutrition & Forestry, Budget & Finance | 6 |
| Pat Roberts | (R-KS) | | 5 | Rules & Administration | Agriculture, Nutrition & Forestry, Finance, Health, Education, Labor & Pensions & Ethics | 9 |
| Jim Risch | (R-ID) | | 5 | Small Business & Entrepreneurship | Energy & Natural Resources, Foreign Relations, Ethics & Intelligence | 1 |
| Richard Burr | (R-NC) | | 4 | Veterans' Affairs | Finance, Health, Education, Labor & Pensions & Intelligence | 2 |
| Thad Cochran | (R-MS) | | 4 | Agriculture, Nutrition & Forestry & Appropriations | Rules & Administration & Joint Committee on the Library | 1 |
| Robert Brady | (D-PA) | | 2 | Administration | Armed Services | 0 |
| Collin Peterson | (D-MN) | | 1 | Agriculture | | 0 |
| Nita Lowey | (D-NY) | | 1 | Appropriations | | 0 |
| Adam Smith | (D-WA) | | 1 | Armed Services | | 0 |
| Chris Van Hollen | (D-MD) | | 1 | Budget | | 0 |
| George Miller | (D-CA) | | 1 | Education & Workforce | | 0 |
| Henry Waxman | (D-CA) | | 1 | Energy & Commerce | | 0 |
| Linda Sanchez | (D-CA) | | 2 | Ethics | Ways & Means | 0 |
| Maxine Waters | (D-CA) | | 1 | Financial Services | | 0 |
| Eliot Engel | (D-NY) | | 2 | Foreign Affairs | Energy & Commerce | 0 |
| Bennie Thompson | (D-MS) | | 1 | Homeland Security | | 0 |
| John Conyers | (D-MI) | | 1 | Judiciary | | 3 |
| Ed Markey | (D-MA) | | 3 | Natural Resources | Small Business & Entrepreneurship & Energy & Commerce | 4 |
| Elijah Cummings | (D-MD) | | 2 | Oversight & Government Reform | Transportation & Infrastructure | 4 |
| Louise Slaughter | (D-NY) | | 1 | Rules | | 0 |
| Eddie Johnson | (D-TX) | | 2 | Science, Space & Technology | Transportation & Infrastructure | 0 |
| Nydia Velazquez | (D-NY) | | 2 | Small Business | Financial Services | 0 |
| Nick Rahall | (D-WV) | | 1 | Transportation & Infrastructure | | 0 |
| Mike Michaud | (D-ME) | | 2 | Veterans' Affairs | Transportation & Infrastructure | 3 |
| Sander Levin | (D-MI) | | 1 | Ways & Means | | 0 |